Studies Of Enantiomeric Separations Using Capillary Electrophoresis
dc.contributor | Tong, Man-Yung Benjamin | en_US |
dc.date.accessioned | 2009-09-16T18:19:42Z | |
dc.date.accessioned | 2011-08-24T21:42:40Z | |
dc.date.available | 2009-09-16T18:19:42Z | |
dc.date.available | 2011-08-24T21:42:40Z | |
dc.date.issued | 2009-09-16T18:19:42Z | |
dc.date.submitted | January 2009 | en_US |
dc.description.abstract | The focus of this thesis is on using state-of-the-art capillary electrophoresis (CE) in enantiomeric separations. Chapter 1 provides a brief introduction to enantiomeric separations using CE. Chapters 2 through 5 presents the use of different novel chiral selectors in CE. The selector properties and strategies for developing on enantiomeric separations are considered. Chapter 2 presents an overview on the most broadly useful chiral selectors for CE enantiomeric separations, sulfated cyclodextrins. Chapter 3 presents a new chiral selector, sodium arsenyl L-(+) tartrate. This chiral selector shows enantioselectivity for many amine-containing compounds and ruthenium (II) polypyridyl complexes and produces electropherograms with short to moderate migration times. Chapter 4 examines the CE enantiomeric separations of ten ruthenium (II) polypyridyl complexes using different types of cyclodextrin chiral selectors. Micellar capillary electrophoresis (MCE) was uilitized in this study. A comparison of the results using MCE to capillary zone electrophoresis (CZE) was discussed. Chapter 5 shows enantiomeric separations of almost 100 different amine-containing compounds using a new chiral selector, sulfated cyclofructan. Separations using the normal and reversed polarity mode were utilized in this study. Results from both separation modes were compared and discussed. | en_US |
dc.identifier.uri | http://hdl.handle.net/10106/1773 | |
dc.language.iso | EN | en_US |
dc.publisher | Chemistry & Biochemistry | en_US |
dc.title | Studies Of Enantiomeric Separations Using Capillary Electrophoresis | en_US |
dc.type | M.S. | en_US |