Developing a diagnostic tool for acyl carrier proteins through trypsinolysis, reverse-phase chromatography and native chemical ligation

Simple item page
dc.contributor.advisorWillets, Katherine A.en
dc.contributor.advisorKeatinge-Clay, Adrian Tristanen
dc.creatorReyes, Graciela, 1957-en
dc.date.accessioned2011-01-06T21:23:43Zen
dc.date.accessioned2011-01-06T21:23:47Zen
dc.date.accessioned2017-05-11T22:21:03Z
dc.date.available2011-01-06T21:23:43Zen
dc.date.available2011-01-06T21:23:47Zen
dc.date.available2017-05-11T22:21:03Z
dc.date.issued2010-08en
dc.date.submittedAugust 2010en
dc.date.updated2011-01-06T21:23:47Zen
dc.descriptiontexten
dc.description.abstractPolyketide biosynthesis is a field that has had tremendous advances in the past 50 years. The understanding of the mechanisms is updated as investigations delve into domain interactions of these microbial natural products. Although numerous polyketides are known, similarities in the sequence of product generation can be used as templates for further exploration of enzymatic activity. The focus of studies recently has been towards developing protocols to manipulate the natural products resulting in medicinally important manufactured products. This investigation examined the mechanism of the acyl carrier protein (ACP) module involved in biosynthesis.en
dc.description.departmentScience and Mathematics Educationen
dc.format.mimetypeapplication/pdfen
dc.identifier.urihttp://hdl.handle.net/2152/ETD-UT-2010-08-1725en
dc.language.isoengen
dc.subjectACPen
dc.subjectProduct generationen
dc.subjectEnzymatic activityen
dc.subjectBiosynthesisen
dc.subjectAcyl carrier proteinen
dc.titleDeveloping a diagnostic tool for acyl carrier proteins through trypsinolysis, reverse-phase chromatography and native chemical ligationen
dc.type.genrethesisen

Files

Collections

University of Texas at Austin