Ultrasound-modulated optical tomography for biomedical applications

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dc.contributorWang, Lihong V.
dc.creatorLi, Jun
dc.date.accessioned2004-11-15T19:53:10Z
dc.date.accessioned2017-04-07T19:49:12Z
dc.date.available2004-11-15T19:53:10Z
dc.date.available2017-04-07T19:49:12Z
dc.date.created2004-08
dc.date.issued2004-11-15
dc.description.abstractI experimentally studied ultrasound-modulated optical tomography, which holds the promise for biomedical diagnosis. I measured the degree of polarization of laser speckles generated by scattered light transmitted through turbid media, investigated three signal-detection schemes for extracting the intensity of the ultrasound-modulated light, carried out experiments to image thick biological-tissue samples, and studied two techniques providing resolution in the cross-sections containing the ultrasonic axis. The study of degree of polarization presented results important for the understanding of polarization phenomena in turbid media. I explored an optical-filtering based signal detection scheme, improved the parallel-lock-in speckle detection scheme and proposed a speckle-contrast detection scheme. With the speckle-contrast detection scheme, I successfully obtained images of biological-tissue samples up to 50 mm thick. Further I studied frequency-swept ultrasound-modulated optical tomography for sub-millimeter resolution imaging, and developed ultrasound-modulated optical computed tomography that was based on a back-projection image reconstruction method and obtained clear images of biological-tissue samples.
dc.identifier.urihttp://hdl.handle.net/1969.1/1274
dc.language.isoen_US
dc.publisherTexas A&M University
dc.subjectultrasound
dc.subjectoptical
dc.subjecttomography
dc.subjectmodulation
dc.subjectbiomedical
dc.titleUltrasound-modulated optical tomography for biomedical applications
dc.typeBook
dc.typeThesis

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