Sample size determination for two sample binomial and Poisson data models based on Bayesian decision theory.

dc.contributor.advisorStamey, James D.
dc.contributor.advisorKahle, David J.
dc.contributor.authorSides, Ryan A.
dc.contributor.departmentStatistical Sciences.en_US
dc.contributor.schoolsBaylor University. Dept. of Statistical Sciences.en_US
dc.date.accessioned2014-01-28T16:00:16Z
dc.date.accessioned2017-04-07T19:34:59Z
dc.date.available2014-01-28T16:00:16Z
dc.date.available2017-04-07T19:34:59Z
dc.date.copyright2013-12
dc.date.issued2014-01-28
dc.description.abstractSample size determination continues to be an important research area in statistical analysis due to the cost and time constraints that often exist in areas such as pharmaceuticals and public health. We begin by outlining the work of a previous article that attempted to find a minimum necessary sample size in order to reach a desired expected power for binomial data under the Bayesian paradigm. We make improvements to their efforts that allow us to specify not only a desired expected Bayesian power, but also a more generic loss function and a desired expected Bayesian significance level, the latter having never been considered previously. We then extend these methodologies to handle Poisson data and discuss challenges in the methodology. We cover a detailed example in both cases and display various results of interest. We conclude by covering a mixed treatment comparisons meta-analysis problem when analyzing Poisson data. Traditional methods do not allow for the presence of underreporting. Here, we illustrate how a constant underreporting rate for all treatments has no effect on relative risk comparisons; however, when this rate changes per treatment, not accounting for it can lead to serious errors. Our method allows this to be taken into account so that correct analyses can be made.en_US
dc.description.degreePh.D.en_US
dc.identifier.urihttp://hdl.handle.net/2104/8922
dc.language.isoen_USen_US
dc.publisheren
dc.rightsBaylor University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact librarywebmaster@baylor.edu for inquiries about permission.en_US
dc.rights.accessrightsWorldwide access.en_US
dc.rights.accessrightsAccess changed 5/31/16.
dc.subjectBayesian sample size determination.en_US
dc.subjectBinomial sample size determination.en_US
dc.subjectPoisson sample size determination.en_US
dc.subjectExpected Bayesian power.en_US
dc.subjectExpected Bayesian significance level.en_US
dc.subjectMixed treatment comparisons meta-analysis.en_US
dc.subjectIndirect comparisons.en_US
dc.subjectUnderreporting in Poisson data models.en_US
dc.titleSample size determination for two sample binomial and Poisson data models based on Bayesian decision theory.en_US
dc.typeThesisen_US

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