Organocatalytic Michael cycloisomerization : studies toward the total synthesis of morphine

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dc.contributor.advisorKrische, Michael J.en
dc.creatorSmith, Ronald Thomasen
dc.date.accessioned2016-03-01T17:04:59Z
dc.date.accessioned2018-01-22T22:29:37Z
dc.date.available2016-03-01T17:04:59Z
dc.date.available2018-01-22T22:29:37Z
dc.date.issued2006-12en
dc.description.abstractThe organocatalytic Michael cycloisomerization has been utilized in both methodological and synthetic chemistry by our research group. This paper investigates the extension of this methodology to other electron deficient alkenes, i.e. nitroalkenes, and their utility in the total synthesis of the classical organic target morphine. The problems and successes encountered en route to the synthetic target as well as the chemistry involved is discussed in detail herein.en
dc.description.departmentChemistryen
dc.format.mediumelectronicen
dc.identifierdoi:10.15781/T2QT2Men
dc.identifier.urihttp://hdl.handle.net/2152/33494en
dc.language.isoenen
dc.relation.ispartofUT Electronic Theses and Dissertationsen
dc.rightsCopyright © is held by the author. Presentation of this material on the Libraries' web site by University Libraries, The University of Texas at Austin was made possible under a limited license grant from the author who has retained all copyrights in the works.en
dc.rights.restrictionRestricteden
dc.subjectDrug synthesisen
dc.subjectElectron deficient alkenesen
dc.subjectMorphine synthesisen
dc.subjectNitroalkenesen
dc.titleOrganocatalytic Michael cycloisomerization : studies toward the total synthesis of morphineen
dc.typeThesisen
dc.type.genreThesisen

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