Fluorescein and Rosamine Derivatives as Donors/Acceptors for "Through-bond" Energy Transfer Cassettes

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dc.contributorBurgess, Kevin
dc.creatorCastro, Juan C.
dc.date.accessioned2010-07-15T00:15:50Z
dc.date.accessioned2010-07-23T21:46:47Z
dc.date.accessioned2017-04-07T19:57:20Z
dc.date.available2010-07-15T00:15:50Z
dc.date.available2010-07-23T21:46:47Z
dc.date.available2017-04-07T19:57:20Z
dc.date.created2009-12
dc.date.issued2010-07-14
dc.description.abstractA series of fluorescein and rosamine derivatives have been prepared and their spectroscopical properties analyzed to determine their usefulness as donor and/or acceptors in "through-bond" energy transfer systems. Such new systems have been tailored to possess higher quantum yields, increased water solubility and higher pH independence. Some of these compounds have also been designed with handles for bioconjugation for use in intracellular imaging. The syntheses of most of these compounds have been optimized to afford higher yields in a multigram scale. Single molecule studies on a fluorescein/rosamine cassette are also reported.
dc.identifier.urihttp://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7574
dc.language.isoeng
dc.subjectFluorescent Cassettes
dc.subjectFluorescein
dc.subjectRosamine
dc.titleFluorescein and Rosamine Derivatives as Donors/Acceptors for "Through-bond" Energy Transfer Cassettes
dc.typeBook
dc.typeThesis

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