Metabolic lipid regulation during developmental stress : fatty acid dynamics in fasting northern elephant seals.

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dc.contributor.advisorTrumble, Stephen John.
dc.contributor.authorRobbins, Kathleen Anne.
dc.contributor.departmentBiology.en_US
dc.contributor.schoolsBaylor University. Dept. of Biology.en_US
dc.date.accessioned2014-06-11T14:08:30Z
dc.date.accessioned2017-04-07T19:35:04Z
dc.date.available2014-06-11T14:08:30Z
dc.date.available2017-04-07T19:35:04Z
dc.date.copyright2014-05
dc.date.issued2014-06-11
dc.description.abstractLong chain fatty acids (LCFA) are important as fuel during exercise in humans, yet have pathological consequences during LCFA overabundance. The northern elephant seal (NES) (Mirounga angustirostris) is a temporally insulin resistant, deep-diving marine mammal reliant on fatty acid oxidation during seasonal fasting. Over the fast, NES females and weaned pups were found to oppositely utilize monounsaturated and saturated fatty acids, while polyunsaturated fatty acids generally increased in both age groups. Fatty acid transporter proteins (FATP) CD36, FATP1, FATP4 and binding protein 3 (FABP3) were detected in adult males, adult females, and pups. This thesis is the first documentation of these FATPs and FABPs in all NES age classes and expands current knowledge of lipid utilization in a mammal accustomed to a LCFA-rich diet.en_US
dc.description.degreeM.S.en_US
dc.identifier.urihttp://hdl.handle.net/2104/9099
dc.language.isoen_USen_US
dc.publisheren
dc.rightsBaylor University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact librarywebmaster@baylor.edu for inquiries about permission.en_US
dc.rights.accessrightsWorldwide accessen_US
dc.subjectFasting.en_US
dc.subjectPhysiology.en_US
dc.subjectMarine mammals.en_US
dc.subjectNorthern elephant seal.en_US
dc.subjectFatty acid.en_US
dc.subjectFatty acid transporter protein.en_US
dc.subjectFatty acid binding protein.en_US
dc.subjectDevelopmental stress.en_US
dc.titleMetabolic lipid regulation during developmental stress : fatty acid dynamics in fasting northern elephant seals.en_US
dc.typeThesisen_US

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