ISKME, a global education research and innovation non-profit, has been collaborating with Texas Higher Education Coordinating Board (THECB) during the last year to leverage findings from the 2019 and 2021 bi-annual Texas OER Landscape Surveys, which were developed by THECB and DigiTex in partnership with ISKME. As part of this work, ISKME has been conducting secondary analyses of regional differences in OER implementation in order to help guide the state’s strategic support of OER within and across regions in Texas. This session will walk through the regional analysis approach and findings from this work, including a summary of regional OER profiles and key factors related to advancing OER programs and policies across institutions. The work has implications for state level strategies for developing programs that can be tailored to a wide range of OER implementation, from early stage to more advanced, and for targeting regions to offer support for using OER in ways that fit regional needs.