Sequence Evolution Of Recurrently Recruited Retroposed Genes In Drosophila And Their Possible Role In Meiotic Drive
| dc.contributor | Tracy, Charles David | en_US |
| dc.date.accessioned | 2009-09-16T18:18:28Z | |
| dc.date.accessioned | 2011-08-24T21:42:22Z | |
| dc.date.available | 2009-09-16T18:18:28Z | |
| dc.date.available | 2011-08-24T21:42:22Z | |
| dc.date.issued | 2009-09-16T18:18:28Z | |
| dc.date.submitted | January 2009 | en_US |
| dc.description.abstract | Gene duplications are a valuable source of genetic information that can evolve under positive selection creating a new gene function without affecting the original function.A gene duplication mechanism is retroposition. Retroposed copies of genes (retrogenes) are created by reverse transcription of a mRNA into the host organism's genome producing a new sequence that has the same protein coding capacity as the parental gene but lacks introns and regulatory regions. <italic>Ran</italic> and <italic>Dntf-2</italic> are genes involved in nuclear transport that have given rise to retrogenes three times in the <italic>Drosophila</italic> genus.Recently, genes involved in nuclear transport such as <italic>Ran</italic> and <italic>Dntf-2</italic> were implicated in playing a major role in a chromosomal segregation distortion system in <italic>D. melanogaster</italic>. This thesis provides evidence of positive selection acting on the retrogenes and discusses the potential role of retroposed nuclear transport genes in segregation distortion. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10106/1697 | |
| dc.language.iso | EN | en_US |
| dc.publisher | Biology | en_US |
| dc.title | Sequence Evolution Of Recurrently Recruited Retroposed Genes In Drosophila And Their Possible Role In Meiotic Drive | en_US |
| dc.type | M.S. | en_US |