Synthetic studies on a model system for the spirobicyclic ring system of oscillatoxin D

Simple item page
dc.creatorJin, Xue-Hui
dc.date.accessioned2016-11-14T23:16:05Z
dc.date.available2011-02-18T20:28:47Z
dc.date.available2016-11-14T23:16:05Z
dc.date.issued1997-05
dc.degree.departmentChemistryen_US
dc.description.abstractThis thesis describes the development of some synthetic methodology applicable to the preparation of the spirobicyclic ring system of the marine natural product oscillatoxin D (1, Figure 1.1). Our goal was to find an efficient way to synthesize a major intermediate for the model compound (2) and thus to provide a guide for the subsequent synthesis of the natural product. Oscillatoxin D has shown some antileukemic activity and it might have undiscovered biological activity. It is a possible drug candidate.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/2346/13943en_US
dc.language.isoeng
dc.publisherTexas Tech Universityen_US
dc.rights.availabilityUnrestricted.
dc.subjectMarine toxinsen_US
dc.subjectNatural productsen_US
dc.subjectOscillatoriaceaeen_US
dc.subjectCyanobacterial toxinsen_US
dc.titleSynthetic studies on a model system for the spirobicyclic ring system of oscillatoxin D
dc.typeThesis

Files

Collections

Texas Tech University