Biosynthesis of sulfur containing heterocycles in natural products
Abstract
This thesis is a comprehensive review of the biosynthesis of sulfur containing heterocycles in natural metabolites. The review focuses on sulfur incorporation and cyclization of the moieties, with a lesser examination of the role these heterocycles play in the chemistry of their compound's activity.
Description
Keywords
Review, Sulfur, Heterocycle, Natural products, Disulfide, Thioether, Peptide, Thiazole, Thiazoline, Thiazolidine, Epipolythiodioxopiperazine, Gliotoxin, Dithiolopyrrolone, Holothin, Romidepsin, Lipoic acid, Tropodithietic acid, Thiotropocin, Asparagusic acid, Lantipeptide, Sactipeptide, Echinomycin, Nosiheptide, Amatoxin, Phallotoxin, Nereistoxin, Gerrardine, Malformin, Trabectedin, Penam, Thiamine, Luciferin, Dercitin, S1319, Violatinctamine, Cepham, Chuangxinmycin, 7-Hydroxy-5-hydroxymethyl-2H-benzo[1,4]thiazin-3-one, Cruciferous phytoalexins, Nasturlexin, Camalexin, Brassinin, Theindolin, Spirobrassinin, Cyclobrassinin, Thiosugar, Kotalanol, Ponkolanol, Salacinol, Salaprinol, Tagetitoxin, Albomycin, Lenthionine, 1,2,3,5-Tetrathiane-5,5-dioxide, Varacin, Lissoclibadin, Cassipoureamide, Caldariellaquinone, Leinamycin, Biotin, Thiolactomycin, Cysteine