Show simple item record

dc.contributor.advisorBrown, E., Sherwood, M.D., Ph.D.
dc.contributor.authorFagan, Colleen Susan
dc.date.accessioned2013-01-17T16:11:04Z
dc.date.accessioned2014-02-19T22:03:39Z
dc.date.available2013-01-17T16:11:04Z
dc.date.available2014-02-19T22:03:39Z
dc.date.issued2013-01-17
dc.identifier.other842004711
dc.identifier.urihttp://hdl.handle.net/2152.5/1245
dc.description.abstractAlthough bipolar disorder and substance dependence are associated with treatment nonadherence and cognitive impairment, few studies have investigated the relationship between treatment adherence and cognitive functioning. Participants in this study were 120 outpatients with bipolar disorder and cocaine dependence enrolled in a 10 week randomized, double-blind, placebo controlled trial of lamotrigine. Baseline performance on the Stroop Color and Word Test and the Rey Auditory Verbal Learning Test were examined for their effect on retention, appointment attendance, medication adherence, and return of medication bottles. Participants with decreased scores on Word condition of the Stroop Color and Word Test were more likely and those with decreased Interference scores were as likely to attend appointments. Participants with better Rey Auditory Verbal Learning Test Total Recall scores returned more medication bottles. Cognitive functioning did not impact medication adherence or study retention. The findings suggest a relationship between cognitive functioning and treatment attendance. Assessment and treatment of cognitive dysfunction may identify and help patients at-risk for treatment nonadherence. Future studies with a more comprehensive neuropsychological test battery and advanced medication adherence measures are warranted.en_US
dc.subjectPatient Compliance
dc.subjectCocaine-Related Disorders
dc.subjectBipolar Disorder
dc.titleThe Impact of Cognition on Treatment Adherence in Comorbid Bipolar Disorder and Cocaine Dependenceen_US
dc.typeThesisen_US
thesis.degree.nameDoctor of Philosophy
thesis.degree.levelPh.D.
thesis.degree.disciplineClinical Psychology
thesis.degree.grantorGraduate School of Biomedical Sciences
thesis.date.available2012-12-20


Files in this item

FilesSizeFormatView
FaganColleen.pdf1.214Mbapplication/pdfView/Open

This item appears in the following Collection(s)

Show simple item record