Browsing by Subject "Mice -- Physiology"
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Item Effect of dietary supplementation of selenium on the immune response in mature male mice(Texas Tech University, 1980-08) Shackelford, JodyNot availableItem Effects of a gram negative bacterin on resistance to Listeria monocytogenes in mice(Texas Tech University, 1981-08) Staraci, Lisa CamilleNot availableItem Effects of deltap9s tetrahydrocannabinol on the immune response in mice(Texas Tech University, 1977-08) Pruess, Mary MNot availableItem In vitro hemolytic studies of selenium compounds and glutathione peroxidase and the effect of dietary selenium on resistance of mice to Klebsiella pneumoniae(Texas Tech University, 1983-05) Hu, Miao-linNot availableItem Resistance to Trypanosoma brucei gambiense among inbred strains of mice(Texas Tech University, 1983-08) Perez, EncarnacionRecent human isolates of Trypanosoma brucei gambiense produce patent low grade to subpatent parasitemias in outbred mice. The purpose of this study was to determine if host genes control resistance to infection. Results of inbred mouse infections indicate that H-2^b and H-2^d haplotypes are resistant, while all H-2^k haplotype mice tested (C3H, AKR, and CE) are susceptible, with death occuring usually in the first peak. Radiation chimeras of resistant and susceptible mice (F1 and parentals), when infected, indicated that immune response genes were responsible for resistance rather than background genes. The indication that H-2^k is linked to susceptibility was proved with congenic BlO.BR/SgSn (H-2^k) mice which were found to be susceptible whereas C57LB/10 (H-2^b) were found to be resistant. Results of infections of F-^ hybrid progeny indicate resistance is dominant and is located on two or more gene loci. Survivors of first peak parasitemias were immunosuppressed and patency rates were determined. These data indicate that there is also a partial H-2 linkage to maintenance of chronic subpatent infections.Item The effects of dietary selenium, silver and methionine on glutathione peroxidase activity and cataracts in mice(Texas Tech University, 1985-05) Brigham, Dale EdwardNot available