Gordon, Cameron, 1945-2012-07-122017-05-112012-07-122017-05-112012-05May 2012http://hdl.handle.net/2152/ETD-UT-2012-05-5055textThis thesis provides a partial classification of all 3-stranded pretzel knots K=P(p,q,r) with unknotting number one. Scharlemann-Thompson, and independently Kobayashi, have completely classified those knots with unknotting number one when p, q, and r are all odd. In the case where p=2m, we use the signature obstruction to greatly limit the number of 3-stranded pretzel knots which may have unknotting number one. In Chapter 3 we use Greene's strengthening of Donaldson's Diagonalization theorem to determine precisely which pretzel knots of the form P(2m,k,-k-2) have unknotting number one, where m is an integer, m>0, and k>0, k odd. In Chapter 4 we use Donaldson's Diagonalization theorem as well as an unknotting obstruction due to Ozsv\'ath and Szab\'o to partially classify which pretzel knots P(2,k,-k) have unknotting number one, where k>0, odd. The Ozsv\'ath-Szab\'o obstruction is a consequence of Heegaard Floer homology. Finally in Chapter 5 we explain why the techniques used in this paper cannot be used on the remaining cases.application/pdfengTopologyKnot theoryUnknotting numberHeegaard Floer homologythesis2012-07-122152/ETD-UT-2012-05-5055