Liu, Hung-wen, 1952-2017-03-242018-01-222017-03-242018-01-222016-12December 2http://hdl.handle.net/2152/46176This thesis is a comprehensive review of the biosynthesis of sulfur containing heterocycles in natural metabolites. The review focuses on sulfur incorporation and cyclization of the moieties, with a lesser examination of the role these heterocycles play in the chemistry of their compound's activity.application/pdfenReviewSulfurHeterocycleNatural productsDisulfideThioetherPeptideThiazoleThiazolineThiazolidineEpipolythiodioxopiperazineGliotoxinDithiolopyrroloneHolothinRomidepsinLipoic acidTropodithietic acidThiotropocinAsparagusic acidLantipeptideSactipeptideEchinomycinNosiheptideAmatoxinPhallotoxinNereistoxinGerrardineMalforminTrabectedinPenamThiamineLuciferinDercitinS1319ViolatinctamineCephamChuangxinmycin7-Hydroxy-5-hydroxymethyl-2H-benzo[1,4]thiazin-3-oneCruciferous phytoalexinsNasturlexinCamalexinBrassininTheindolinSpirobrassininCyclobrassininThiosugarKotalanolPonkolanolSalacinolSalaprinolTagetitoxinAlbomycinLenthionine1,2,3,5-Tetrathiane-5,5-dioxideVaracinLissoclibadinCassipoureamideCaldariellaquinoneLeinamycinBiotinThiolactomycinCysteineThesis2017-03-24