Now showing items 1-5 of 5

    • Apoptosis Determinants in Drosophila melanogaster 

      Chew, Su Kit (2007-12-17)
      Apoptosis is a form of programmed cell death (PCD) that is governed by a core set of genes conserved across diverse metazoan phyla. Cells dying by apoptosis exhibit a characteristic series of morphological and biochemical ...
    • Bcl-2 Function in Drosophila 

      Galindo, Kathleen A. (2007-12-17)
      Bcl-2 family members are pivotal regulators of programmed cell death (PCD). In mammals, pro-apoptotic Bcl-2 family members initiate early apoptotic signals by causing the release of cytochrome c from the mitochondria, a ...
    • Biochemical Analysis of Apoptosome Formation 

      Kim, Hyun-Eui (2006-12-19)
      Apoptosis is an active cell death program executed by proteases named caspases. One of the major caspase-activating pathways is initiated by mitochondria. Upon various apoptotic stimuli, the mitochondria releases cytochrome ...
    • Communal Cell Death and P53 Mediated Transcriptional Control in Drosophila Melanogaster 

      Link, Nichole Lynn (2011-08-26)
      Apoptosis is essential for all metazoan development. The key component that functions in apoptosis, the apoptosome, is a molecular machine that initiates caspase activation and is conserved throughout the animal kingdom. ...
    • Illuminating the P53 Regulatory Network in Genetic Models 

      Lu, Wan-Jin (2011-02-01)
      The tumor suppressor gene p53 is mutated in more than 50% of human cancers, and functions as a central component of stress response machinery that mediates a wide variety of downstream responses. Interestingly, the ...