Browsing University of Texas Medical Branch by Title
Now showing items 104-123 of 285
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Gastrin-releasing peptide-mediated neuroblastoma growth: A role for the PI3K/Akt pathway
(2008-12-18)Neuroblastoma is the most common extracranial solid tumor in infants and children. Our lab and others have shown trophic actions of gastrin-releasing peptide (GRP), and its analogue bombesin (BBS), in neuroblastomas. Our ... -
Gene expression microarray analysis of small, purified cell subsets
(2007-04-23)Gene expression microarray technology is potentially capable of examining all of the cellular processes at the mRNA level at a given moment. One major challenge in its applicability is that most biological samples are cell ... -
General physical preparedness of emergency and essential personnel
(2010-07-12)Emergency and disaster preparedness plans are an essential requirement for most organizations today due to the frequency and complexity of incidents such as disease outbreaks, natural disasters such as hurricanes, floods, ... -
A general scaffold for the synthesis of cysiherbaine and its analogues
(2008-12-03)Dysiherbaine 1 and a select number of structurally related compounds have been shown to have selective effects on ionotropic glutamate receptors (iGluRs). iGluRs are essential components in the central nervous system (CNS); ... -
Genetic determinants of NEIL2 transcription
(2008-03-20)The human genome is constantly damaged by reactive oxygen species (ROS) which produce a multitude of oxidative DNA lesions that can lead to mutations, genomic instability, and ultimately, to the development of cancer and ... -
Genetic diversity and taxonomical relationships among the tacaribe serocomplex viruses (family arenaviridae)
(2007-05-30)The three objectives of this dissertation were to 1) examine the natural host relationships and origins of the North American Tacaribe serocomplex viruses (family Arenaviridae), 2) extend our knowledge of the genetic ... -
Giving voice to the vulnerable: Advocacy and oncology nursing
(2008-07-24)Despite common use of the term, there is no consensus among nursing professionals on a definition of advocacy, how to teach it, measure it, and determine its effectiveness. The purpose of this grounded theory study was to ... -
GOUT: An aeromedical clinical practice guideline
(2008-04-21)Through the completion of this capstone project, I am demonstrating the significance of gout in the United States of America, and in particular in the arena of aerospace medicine today. I have created a current clinical ... -
A grounded theory study of substance use patterns among homeless youth
(2009-07-13)A Grounded Theory Study of Substance Use Patterns among Homeless Youth\r\n\r\nPublication No.______________\r\nPhilisie Starling Washington, PhD\r\nThe University of Texas Medical Branch, 2009\r\n\r\nSupervisor: Carolyn ... -
Hearing assessment aboard the International Space Station
(2010-09-15)This study undertakes to refine the understanding of the accuracy of a novel PC-based hearing assessment utilized aboard the International Space Station. During the design and construction of the ISS, time and funding ... -
HEM-protein regulates cell migration and asymmetric cell division during development of the ventral nerve cord in Drosophila melanogaster
(2010-07-08)Cell migration and asymmetric cell division are two of the key events during development of the nervous system. I have focused on a typical neuronal lineage, NB4-2→GMC-1→RP2/sib, in the ventral nerve cord (VNC) of the ... -
Hospital depressive symptoms and ADL disability in older adults: A longitudinal analysis of course and associations
(2010-04-26)Depressive symptoms and disability in activities of daily living (ADL) often increase in older adults during hospitalization and for many persist post-discharge. However, little is known about the psychological and functional ... -
Host cell signaling in response to RSV infection
(2008-04-14)RSV infection is the most important cause of hospitalization of infants, and is also the major cause for admissions in adults with chronic cardiac disease and pulmonary diseases. So far, there is no effective treatment or ... -
Host response of lung cells to virulent Bacillus anthracis
(2008-11-24)Bacillus anthracis, the etiological agent of anthrax, is a Gram-positive, spore-forming bacterium that is classified as a Category A select agent. The current paradigm in anthrax literature labels the alveolar macrophage ... -
Humna fetal neural stem cells: Proliferation and differentiation in response to growth factors and role in locomotor recovery after spinal cord contusion injury
(2005-01-12)Human fetal neural stem cells (hNSCs) may be useful for developing a cell-based therapy to treat spinal cord injury (SCI). In these studies we examined the effects of epigenetic mitogens on proliferation and differentiation ... -
\"ICE\" awareness among local EMS personnel
(2008-07-10)‘ICE’ stands for ‘in case of emergency.’ The ICE concept is simply to have people program their emergency contact information into their cell phone contact list under the acronym ‘ICE.’ In this way rescuers on a scene ... -
Identificaiton of the pore-lining helices of connexin 43 gap-junctional hemichannels
(2008-03-28)The gap-junctional channels that mediate intercellular communication are formed by head-to-head docking of two gap-junctional hemichannels from adjacent cells. The hemichannels are hexamers of connexins, proteins that have ... -
Identification and characterization of cell-adapted mutations in West Nile Virus and replicons
(2007-12-19)Flavivirus persistence in cell culture is achieved by altering the interaction between the viral genome and the host cell. To identify some of the factors that contribute to a persistent West Nile virus (WNV) infection, ... -
Identification and Characterization of Effectors/Binding Molecules for the Small GTPase Rab15
(2005-03-18)Endocytic trafficking is a key mechanism for regulating receptor availability on\r\nthe plasma membrane as well as receptor degradation. Clathrin-dependent endocytosis\r\ninvolves receptor internalization into early ... -
If walls could talk: The lived experience of witnessing verbal abuse toward residents in long-term care facilities.
(2007-10-19)Twenty percent of the population over 65 years of age will spend some time in a nursing home. Most research addressing abuse in long-term care (LTC) facilities focus on sexual abuse, physical abuse and financial abuse or ...