University of Texas Medical Branch

Understanding the assembly of simple ssRNA virus nucleocapsids

Lamb, Kristen (2010-08-28)

The assembly of simple ssRNA viruses from the initial interactions critical for nucleocapsid formation until the morphogenesis which occurs at each maturation stage of the virus’s “life” can entail a wide range of possibilities ...

The Role of Sacsin as a Molecular Chaperone

Anderson, John (2013-06-03)

The central pathological finding in neurodegenerative disease is loss of neurons. In many disorders, this loss of neurons appears to be related to protein misfolding, comprising a large public health burden. For example, ...

ORGAN DONATION IN THE UNITED STATES

Basraon, Jaswant (2013-06-03)

Introduction: The demand for donor organs far exceeds the number of donors. Approximately 18 people in the United States die every day waiting for an organ transplant. The purpose of this capstone is to describe the ...

Molecular Pathogenesis of Spinocerebellar Ataxia type 10

Lim, Jung gook 1971- (2013-06-03)

Spinocerebellar ataxia type 10 (SCA10) is a unique autosomal dominant cerebellar ataxia (ADCA) which habors non-coding ATTCT repeat expansion on the 9th intron of the ATXN10 gene. The presence of seizure in addition to ...

Molecular Pathogenesis of Spinocerebellar Ataxia type 10

Lim, Jung gook (2013-06-03)

Microsatellite plays a major pathogenic role in repeat expansion disorder. This heterogeneous group of disease is caused by the expanded sequences of nucleotide repeat within a target gene. Spinocerebellar ataxia type 10 ...

Novel Insights Into Normal Aryl Hydrocarbon Receptor Biology Through the Regulation of Stanniocalcin 2

Harper, Tod 1982- (2013-06-03)

Proper hepatocyte function is vital for survival; hence unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver ...

Studies on Fortilin-Prohibitin Interaction

Doan, Hung 1982- (2013-06-03)

Abstract: Apoptosis, programmed cell death, is a tightly regulated process that occurs in development, in tissue maintenance and turnover, and in regulating the immune system. Alterations in apoptosis regulation is known ...

Behaving Collaboratively and Getting Along: A Classical Grounded Theory of Certified Nurse Midwives Collaborating With Physicians in U.S. Hospitals

Nilsen, Susan 1958- (2013-06-03)

This dissertation is a classical grounded theory study that examines how certified nurse midwives perceive their collaborative role as they work with physicians in U.S. hospitals. The most common reason for hospitalization ...

MOLECULAR INSIGHTS AND PHYSIOLOGICAL CONSEQUENCES OF ARYL HYDROCARBON RECEPTOR REGULATED PLASMINOGEN ACTIVATOR INHIBITOR-1 EXPRESSION

Wilson, Shelly (2013-06-03)

The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, attenuates liver regeneration in vivo when activated by its prototypical agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) following 70% partial ...

Discovering the Current Wound Management Practices of Rural Africans: a Pilot Study

Benskin, Linda 1959- (2013-06-03)

Unrelenting heat, poor sanitation, lack of knowledge, and poverty contribute to a disabling wound prevalence that often exceeds 20% in rural areas of tropical developing countries. Wounds in this environment are usually ...

Inpatient Rehabilitation Outcomes for Patients with Debility

Galloway, Rebecca 1977- (2013-06-03)

Background: Inpatient rehabilitation facility (IRF) goals are to optimize functional independence and discharge patients to community living. Debility, or deconditioning associated with hospitalization, is the fourth ...

Impact of Diabetes Comorbidity on Health Outcomes in Patients Undergoing Medical Rehabilitation after Lower Extremity Joint Arthroplasty

Karmarkar, Amol (2013-06-03)

Introduction: Diabetes is one of the rapidly increasing chronic conditions that can impact the health and well-being of individuals. Objectives: To determine the prevalence of diabetes in patients receiving medical ...

Inpatient Rehabilitation Outcomes for Patients with Debility

Galloway, Rebecca 1977- (2013-06-03)

Background: Inpatient rehabilitation facility (IRF) goals are to optimize functional independence and discharge patients to community living. Debility, or deconditioning associated with hospitalization, is the fourth ...

Post Traumatic Story Disorder: Using the Power of Narrative to Heal the Invisible Wounds of War

Genovese, Jacqueline 1964- (2013-06-03)

Abstract Soldiers traumatized by war often experience debilitating effects of invisible wounds such as post-traumatic stress disorder (PTSD). An obstacle to recovery from PTSD for male soldiers can be an inability to share ...

Tuberculosis: Epidemiology, Diagnosis, Treatment, Prevention and Control in the United States and Worldwide

Calderon, Veronica Elena (2013-06-03)

TB is one of the most common infectious diseases worldwide. Approximately one-third of the world’s population is infected with TB. In 2011, there are about 9 million new infections and almost 1.4 million deaths. Furthermore, ...

CHEMICAL MIXTURES OF XENOESTROGENS AND THEIR METABOLITES ALTER ESTRADIOL-INDUCED NON-GENOMIC SIGNALING

Vinas, Rene (2013-06-03)

BACKGROUND: Xenoestrogens (XEs) pose a threat to human health by disrupting natural responses of physiologic estrogens. Bisphenol-A (BPA), a plastics monomer, is potently estrogenic via non-genomic signaling; however, ...

Evaluation of granulysin and perforin as candidate biomarkers for protection following vaccination with Mycobacterium bovis BCG or M. bovis DeltaRD1

Charles Fernando Capinos Scherer (2008-09-18)

The development of improved vaccines against tuberculosis (TB) is directly linked to the investigation of new and better correlates of protection after vaccination against TB. Cloning and characterization of bovine homologues ...