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dc.contributor.advisorBull, James J.en
dc.contributor.advisorWilke, C. (Claus)en
dc.contributor.committeeMemberJuenger, Thomasen
dc.contributor.committeeMemberMeyers, Lauren Aen
dc.contributor.committeeMemberSawyer, Sara Len
dc.creatorKeller, Thomas E.en 2012en
dc.description.abstractIn my dissertation I have broadly studied the evolution of RNA as well as the phylogenetic history of the actin protein family. In the first chapter I examined how various evolutionary processes interact at high mutation rates, which led to simple prediction based on the strength of selection. In the second chapter, I tested mRNA secondary structure stability at the beginning of genes as a way of identifying whether putative genes might be functional or not. Finally, I reconstructed the phylogenetic history of the actin protein family in vertebrates, revealing that a novel isoform is actively evolving in contrast to the remaining protein isoforms.en
dc.subjectHigh mutation ratesen
dc.subjectActin phylogenyen
dc.titleThe evolution of RNA and the actin protein familyen
dc.description.departmentEcology, Evolution and Behavioren

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